Assisi, the Holy City for the Christians, is always the destination for those pilgrims who want to see the places where Saint Francis was born, was active, and where, near the Porziuncola, he died on October 4th, 1226.
You can go to Assisi:
Exit to Assisi - Santa Maria degli Angeli)
the railway line Perugia-Foligno-Rome, getting off to the station of Assisi
the airport of Sant'Egidio in Perugia